2025–2034 horizon (10y)
Module 1
Market Foundation
Editable source of truth for Chronic weight management in adults with obesity. Every edit flows into the forecast, scenarios, and snapshots downstream.
All values at seeded defaults. Click any cell to edit.
AI Foundation Review
Grades each row against 0 chunks across 0 documents + house view.
Grade every segment and channel against the pinned + uploaded evidence library. Returns supported / contradicted / stale / no-evidence per row, with verbatim citations. Upload at least one document in the Evidence Library to run this.
Patient segments
Sizing, share, persistence, and per-segment access friction (new vs continuing) — per brief §2.
Access impact sourceHeuristic— replace with claims-derived curves to anchor.
| Segment | Diagnosed (M) | Treatment rate | Max share | Access impact · new | Access impact · cont. | New persistence | Cont. persistence | |
|---|---|---|---|---|---|---|---|---|
BMI ≥30 w/ comorbidity Obesity with T2D, HTN, dyslipidemia | % | % | % | % | % | % | ||
BMI ≥30 uncomplicated Obesity without qualifying comorbidity | % | % | % | % | % | % | ||
BMI 27–29.9 w/ comorbidity Overweight with qualifying comorbidity | % | % | % | % | % | % | ||
Established CVD (SELECT) Secondary CV risk reduction label | % | % | % | % | % | % | ||
Adolescent obesity Ages 12–17 with BMI ≥95th %ile | % | % | % | % | % | % |
Manual rows give you full control. AI suggestions draft starter rows from your uploaded docs + House View — review and accept individually.
Payer channels
Channel mix, baseline access, GTN, WAC, and annual WAC/rebate drift over the horizon (brief §2).
| Channel | Mix | Baseline access | GTN | WAC ($/mo) | WAC growth /yr | Rebate drift /yr | PBM admin fee | |
|---|---|---|---|---|---|---|---|---|
Commercial | % | % | % | % | % | % | ||
Self-insured / carve-out | % | % | % | % | % | % | ||
Medicare Part D | % | % | % | % | % | % | ||
Medicare Advantage | % | % | % | % | % | % | ||
Medicaid (FFS+MCO) | % | % | % | % | % | % | ||
Cash / 340B | % | % | % | % | % | % |
Key business questions
The issue map. Every downstream driver and assumption ties back to one of these. Add custom KBQs below — they flow into the issue map and coverage-gap flag.
House view
The team's framing doc that's injected into every AI call. Lives with the rest of the grounding stack.
House view and source documents live in the Evidence Library — both are AI grounding context, not quant inputs. The Foundation Review above cites the relevant chunks per row.