20252034 horizon (10y)
Module 4

Strategy Simulator

Pick a scenario, then see which strategy plays hold up. The forecast engine is unchanged — lever choices annotate access and risk, not the core math.

Access Compression: PBM tightening accelerates, employer carve-outs spread, oral GLP-1 takes share faster than expected.
Strategy levers
Net price posturerecommended
Contracting modelrecommended
Patient support investment
Evidence generation
Channel focus
Supply allocation
Access Compression · peak net revenue
$12.64B
67.4%
Base $7.55B · Y2034
Strategy fit
100%
2/6 levers match recommended play
Execution risk
55%
Risk-neutral or risk-reducing
Directional strategy matrix

How each lever option moves the model under Access Compression. ↑ improves, ↓ erodes, ↔ neutral.

Lever / optionAccessGTNRiskSelected
Net price posture
Hold WAC, deepen rebatesrec
Net price posture
WAC cut 10%
Net price posture
Hold WAC, flat rebate
Contracting model
Traditional rebate
Contracting model
Outcomes-based (HbA1c/MACE)rec
Contracting model
Indication-based pricing
Patient support investment
Maintain current
Patient support investment
Expand bridge program
Patient support investment
Income-tested copay assistancerec
Evidence generation
Maintain current
Evidence generation
RWE for employer ROI
Evidence generation
Pragmatic trial in CV subgrouprec
Channel focus
Broad commercial
Channel focus
Cardiology lift
Channel focus
Employer directrec
Supply allocation
Pro-rata across channels
Supply allocation
Prioritize commercialrec
Supply allocation
Prioritize Medicare-eligible
Portability across scenarios

Same strategy mix, re-scored against every scenario. A robust play stays positive across all three.

Base Case
43.9%risk -17
Access Compression
67.4%risk -17
CV Label Expansion
34.3%risk -17
AI narrative · Access Compression
Under Access Compression, the current mix produces 67.4% lift vs the scenario base and matches 2 of 6 recommended plays.
Click Generate for a grounded AI narrative. The model receives only the structured numbers and selections shown on this page.